JB LAB

​

66.   Manchanda, Y.; Bitsi, S.; Chen, S.; Broichhagen, J.; de la Serna, J. B.; Jones, B.; Tomas, A., Enhanced endosomal signaling and desensitization of GLP-1R versus GIPR in pancreatic beta cells, Endocrinology 2023, doi: 10.1210/endocr/bqad028.

​

65.   Jain, A.; Broichhagen, J.*, Make it stick: fixable ligands for tissue imaging, Chem 2023, 9, 260–262. 

​

64.   Ast, J.; Nasteska, D.; Fine N. H. F.; Nieves, D.; Koszegi, Z.; Lanoiselée, Y.; Cuozzo, F.; Viloria, K.; Bacon, A.; Luu, N.-T.; Newsome, P. N.; Calebiro, D.; Owen, D.; Broichhagen, J.*; Hodson, D. J.*, Revealing the tissue-level complexity of endogenous glucagon-like peptide 1-receptor expression and signaling, Nat. Commun. 2023, 14, 301.

​

63.   Jatzlau, J.; Burdzinski, W.; S.; Trumpp, M.; Obendorf, L.; Roßmann, K.; Ravn, K.; Hyvönen, M.; Bottanelli, F.; Broichhagen, J.; Knaus, P., A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding, Commun. Biol. 2023, 6, 34. 

​

62.   Trumpp, M.; Oliveras, A.; Gonschior, H.; Ast, J.; Hodson, D. J.; Knaus, P.; Lehmann, M.; Birol, M.*; Broichhagen, J.*, Enzyme self-label-bound ATTO700 in single-molecule and super-resolution microscopy, Chem. Commun. 2022, 58, 13724–13727.

​

61.   Xiang, G.; Acosta-Ruiz, A.; Radoux-Mergault, A.; Kristt, M.; Kim, J.; Moon, J. D.; Broichhagen, J.; Inoue, A.; Lee, F. S.; Stoeber, M.; Dittman, J. S.; Levitz, J., Control of Gaq signaling dynamics and GPCR cross-talk by GRKs, Sci. Adv. 2022, 8, eabq3363.

​

60.   Stieger, C. E.; Park, YT.; de Geus, M. A. R.; Kim, D.; Huhn, C.; Slenczka, J. S.; Ochtrop, P.; Müchler, J. M.; Süssmuth, R.; Broichhagen, J.; Baik, M.-H.; Hackenberger, C. P. R., DFT-guided Discovery of Ethynyl-Triazolyl-Phosphinates for Chemoselective Cysteine Bioconjugation and Profiling, Angew. Chem. Int. Ed. 2022, 61, e202205348.. 

​

59.   Roßmann, K.; Akkaya, K. C.; Poc, P.; Charbonnier, C.; Eichhorst, J.; Gonschior, H.; Valavalkar, A.; Wendler, N.; Cordes, T.; Dietzek-Ivanšić, B.; Jones, B.; Lehmann, M.; Broichhagen, J.*, N-Methyl deuterated rhodamines for protein labelling in sensitive fluorescence microscopy, Chem. Sci. 2022, 13, 8605–8617.

​

58.   Berry, M.; Holt, A.; Broichhagen, J.; Donthamsetti, P.; Flannery, J. G.; Isacoff, E. Y., Photopharmacology for vision restoration, Curr. Opin. Pharmacol. 2022, 65, 102259.

​

57.   Huhn, C.; Broichhagen, J.*, Visualisierung endogener Proteine in ihrer natürlichen Umgebung, Biospektrum (Heidelb.) 2022, 3, 264–268.

​

56.   Cahill, K. N.; Amin, T.; Boutaud, O.; Printz, R.; Newcomb, D.; Hodson, D. J.; Broichhagen, J.; Beckman, J.; Mashayekhi, M.; Luther, M.; Brown, N.; Peebles, R. S.; Niswender, K., Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation, JACC: Basic Transl. Sci. 2022, accepted.

​

55.   Ast, J.; Novak, A. N.; Podewin, P.; Fine, N. H. F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B.; Eichhorst, J.; Lehmann, M.; Linnemann, A. K.*; Hodson, D. J*.; Broichhagen, J.*, An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo, JACS Au 2022, 2, 1007–1017. 

​

54.   Mugabo, Y.; Zhao, C.; Tan, J. J.; Ghosh, A.; Campbell, S. A.; Fadzeyeva, E.; Paré, F.; Pan, S. S.; Galipeau, M.; Ast, J.; Broichhagen, J.; Hodson, D. J.; Mulvihill, E. E.; Petropoulos, S.; Lim, G. E., 14-3-3ζ constrains insulin secretion by regulating mitochondrial function in pancreatic β-cells, JCI Insight 2022, 7, e156378. .

​

53.   Broichhagen, J.*; Levitz, J.*, Advances in tethered photopharmacology for precise optical control of signaling proteins, Curr. Opin. Pharmacol. 2022, 63, 102196.

​

52.   Gazzi, T.; Brennecke, B.; Atz, K.; Korn, C.; Sykes, D.; Forn-Cuni, G.; Pfaff, P.; Sarott, R. C.; Westphal, M. V.; Mostinski, Y.; Mach, L.; Wasinska-Kalwa, M.; Weise, M.; Hoare, B. L.; Miljuš, T.; Mexi, M.; Roth, N.; Koers, E. J.; Guba, W.; Alker, A.; Rufer, A. C.; Kusznir, E. A.; Huber, S.; Raposo, C.; Zirwes, E. A.; Osterwald, A.; Pavlovic, A.; Moes, S.; Beck, J.; Nettekoven, M.; Benito-Cuesta, I.; Grande, T.; Drawnel, F.; Widmer, G.; Holzer, D.; van der Wel, T.; Mandhair, H.; Grimsey, N.; Honer, M.; Fingerle, J.; Scheffel, J.; Broichhagen, J.; Gawrisch, K.; Romero, J.; Hillard, C. J.; Varga, Z. V. van der Stelt, M.; Pacher, P.; Gertsch, J.; Ullmer, J.; McCormick, P. J.; Oddi, S.; Spaink, H. P.; Maccarrone, M.; Veprintsev, D. B.; Carreira, E. M.; Grether, U.; Nazaré, M., Detection of Cannabinoid Receptor Type 2 in Native Cells and Zebrafish with a Highly Potent, Cell-Permeable Fluorescent Probe, Chem. Sci. 2022, 13, 5539–5545.

​

51.   Pauza, A. G., Thakkar, P.; Tasic, T.; Felippe, I.; Bishop, P.; Greenwood, M. P.; Rysevaite-Kyguoliene, K.; Ast, J.; Broichhagen, J.; Hodson, D. J.; Salgado, H. C.; Pauza, D. H.; Japundzic-Zigon, N.; Paton, J. F. R.; Murphy, D., GLP1R attenuates sympathetic response to high glucose via carotid body inhibition, Circ. Res. 2022, 130, 694–707.

​

50.   Birke, R.; Ast, J.; Roosen, D. A.; Lee, J.; Roßmann, K.; Huhn, C.; Mathes, B.; Lisurek, M.; Bushiri, D.; Sun, H.; Jones, B.; Lehmann, M.; Levitz, J.; Haucke, V.; Hodson, D. J.; Broichhagen, J.*, Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins, Org. Biomol. Chem. 2022, doi: 10.1039/D1OB02216D.

​

49.   Ast, J.; Broichhagen, J.*; Hodson, D. J.*, Reagents and models for detecting endogenous GLP1R and GIPR, EBioMedicine 2021, 74, 103739.

​

48.   Selvakumar, P.; Lee, J.; Khanra, N.; He, C.; Munguba, H.; Kiese, L.; Broichhagen, J.; Reiner, A.; Levitz, J.; Meyerson, J. R., Structural and compositional diversity in the kainate receptor family, Cell Rep. 2021, 37, 109891.

​

47.   Kemter, E.; Müller, A.; Neukam, M.; Ivanova, A.; Klymiuk, N.; Renner, S.; Yang, K.; Broichhagen, J.; Kurome, M.; Zakhartchenko, V.; Kessler, B.; Knoch, K.-P.; Bickle, M.; Ludwig, B.; Johnsson, K.; Lickert, H.; Kurth, T.; Wolf, E.; Solimena, M., Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs, Proc. Natl. Acad. Sci. USA 2021, 118, e2107665118. 

 

46.   Lucey, M.; Ashik, T.; Marzook, A.; Wang, Y.; Goulding, J.; Oishi, A.; Broichhagen, J.; Hodson, D. J.; Minnion, J.; Elani, Y.; Jockers, R.; Briddon, J. B.; Bloom, S. R.; Tomas, A.; Jones, B., Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking, Mol. Pharmacol. 2021, 100, 319–334. 

​

45.    Olaniru, O. E.; Cheng, J.; Ast, J.; Arvaniti, A.; Atanes, P.; Huang C. G.; King, A. J. F.; Jones, P. M.; Broichhagen, J.; Hodson, D. J.; Persaud, S. J., SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells, Mol. Metab. 2021, 53, 101285.

​

44.    Marzook, A.; Chen, S.; Pickford, P.; Lucey, M.; Wang, Y.; Corrêa Jr, I.; Broichhagen, J.; Hodson, D. J.; Salem, V.; Rutter, G. A.; Tan, T. M.; Bloom, S. R.; Tomas, A.; Jones, B., Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1, Biochem. Pharmacol. 2021, 190, 114656.

 

43.   Khelashvili, G.; Pillai, A. N.; Lee, J.; Pandey, K.; Payne, A. M.; Siegel, Z.; Cuendet, M. A.; Lewis, T. Y.; Arshavsky, V. Y.; Broichhagen, J.; Levitz, J.; Menon, A. K., Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin, Sci. Rep. 2021, 11, 10536. 

​

42.   Thibado, J. K.; Tano, J.-Y.; Lee, J.; Salas-Estrada, L.; Provasi, D.; Strauss, A.; Ribeiro, J. M. L.; Xiang, G.; Broichhagen, J.; Filizola, M.; Lohse, M.; Levitz, J., Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors, eLife 2021, 10, e67027.

​

41.   Gutzeit, V. A.; Acosta-Ruiz, A.; Munguba, H.; Häfner, S., Landra-Willm, A.; Mathes, B.; Mony, J.; Yarotski, D.; Börjesson, K.; Liston, C.; Sandoz, G.; Levitz, J.; Broichhagen, J.*, A fine-tuned azobenzene for enhanced photopharmacology in vivo, Cell Chem. Bio. 2021, in press, https://doi.org/10.1016/j.chembiol.2021.02.020

​

40.   Broichhagen, J.#,*; Kilian, N.#,*, Chemical biology tools to investigate malaria parasites, ChemBioChem 2021, 22, 2219–2236. 

​

39. PhotocagedHoechst enables subnuclear visualization and cell selective staining of DNA in vivo, Lämmle, C. A.; Varady, A.; Müller, T. G.; Sturtzel, C.; Riepl, M.; Mathes, B.; Eichhorst, J.; Sporbert, A.; Lehmann, M.; Kräusslich, H.-G.; Distel, M.; Broichhagen, J.*, ChemBioChem 2021, 22, 548–556. 

​

38. Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells, Fang, Z.; Chen, S.; Manchanda, Y.; Bitsi, P.; Pickford, P.; David, A.; Shchepinova, M. M.; Corrêa Jr, I.; Hodson, D. J.; Broichhagen, J.; Tate, E. W.; Reimann, F.; Salem, V.; Rutter, G. A.; Tan, T.; Bloom, S. R.; Tomas, A.; Jones, B. J., Int. J. Mol. Sci. 2020, 21, 8404. 

​

37. Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPARg), Hinnah, K.; Willems, S.; Morstein, J.; Heering, J.; Hartrampf, F. W. W.; Broichhagen, J.; Leippe, P.; Merk, D.; Trauner, D., J. Med. Chem. 2020, 63, 10908–10920.

​

36. Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates, Poc, P.; Gutzeit, V. A.; Ast, J.; Joon, L.; Jones, B. J.; D’Este, E.; Mathes, B.; Lehmann, M.; Hodson, D. J.; Levitz, J.; Broichhagen, J.*, Chem. Sci. 2020, 11, 7871–7883. 

​

35. Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide, Pickford, P.; Lucey, M.; Fang, Z.; Bitsi, S.; Bernardino de la Serna, J.; Broichhagen, J.; Hodson, D. J.; Minnion, J.; Rutter, G. A.; Bloom, S. R.; Tomas, A.; Jones, B. J., Br. J. Pharmacol. 2020, 117, 7871–7883.

​

34. The influence of peptide context on signalling and trafficking of glucagon-like peptide-1 receptor biased agonists, Fang, Z.; Chen, S.; Pickford, P.; Broichhagen, J.; Hodson, D. J.; Corrêa Jr, I.; Kumar, S.; Görlitz, F.; Dunsby, C.; French, P.; Rutter, G. A.; Tan, T.; Bloom, S. R.; Tomas, A.; Jones, B. J., ACS Pharmacol. Transl. Sci. 2020, 3, 345–360. 

​

33. Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors, Leippe, P.#; Broichhagen, J.#; Cailliau, K.; Mougel, A.; Morel, M.; Dissous, C.; Trauner, D.; Vicogne, J., Angew. Chem. Int. Ed. 2020, 59, 6720–6723.

​

32. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics, Ast, J.; Arvaniti, A.; Fine N. H. F.; Nasteska, D.; Ashford, F.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B. J.; Lucey, M. A.; Sasaki, S.; Hastoy, B.; Tomas, A.; Reiman, F.; D’Agostino, G.; Reiman, F.; Lynn, F. C.; Reissaus, C.; Linnemann, A. K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.*; Broichhagen, J.*; Hodson, D. J.*, Nat. Commun. 2020, 11, 467.

​

31. Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo, Acosta-Ruiz, A.; Gutzeit, V. A.; Skelly, M. J.; Meadows, S.; Lee, J.; Parekh, P.; Orr, A. G.; Liston, C.; Pleil, K. E.; Broichhagen, J.*; Levitz, J.*, Neuron 2020, 105, 446–463.

​

30. Genetically-targeted optical control of an endogenous G protein-coupled receptor, Donthamsetti, P. C.; Broichhagen, J.; Vyklicky, V.; Stanley, C.; Fhu, Z.; Visel, M.; Levitz, J.; Javitch, J. A.; Trauner, D.; Isacoff, E. Y., J. Am. Chem. Soc. 2019, 141, 11522–11530.

​

29. CCDC 1884029: Experimental Crystal Structure Determination, Broichhagen, J.; Burg, F.; Häfner, S.; Mayer, P.; Trauner, D., CSD Communication 2018, https://doi.org/10.5517/ccdc.csd.cc217h4y.

​

28. Optical tools for understanding the complexity of beta cell signaling and insulin release, Frank, J. A.#, Broichhagen, J.#; Yushchenko, D.; Schultz, C.; Trauner, D.; Hodson, D. J., Nat. Rev. Endocrinol. 2018, 14, 721–737.

​

27. SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand, Farrants, H.; Acosta-Ruiz, A.; Gutzeit, V. A.; Trauner, D.; Johnsson, K.; Levitz, J.*; Broichhagen, J.*, ACS Chem. Bio. 2018, 13, 2682–2688.

​

26. A New Fluorogenic Small-Molecule Labeling Tool for Surface Diffusion Analysis and Advanced Fluorescence Imaging of β-site Amyloid Precursor Protein-Cleaving Enzyme 1 Based on Silicone Rhodamine: SiR-BACE1, Karch, S.#, Broichhagen, J.#; Schneider, J.#; Böning, D.; Hartmann, S.; Schmid, B.; Tripal, P.; Palmisano, R.; Alzheimer, C.; Johnsson, K.; Huth, T., J. Med. Chem. 2018, 61, 6121–6139.

​

25. A (+)-larixol congener with high affinity and subtype selectivity towards TRPC6, Häfner, S.; Burg, F.; Kannler, M.; Urban, N.; Mayer, P.; Dietrich, A.; Trauner, D.*; Broichhagen, J.*; Schaefer, M.*, ChemMedChem 2018, 13, 1028–1035.

​

24. A predictive approach for the optical control of carbonic anhydrase II activity, DuBay, K. H.; Iwan, K.; Osorio-Planes, L.; Geissler, P.; Groll, M.; Trauner, D.; Broichhagen, J.*, ACS Chem. Bio. 2018, 13, 793–800.

​

23. Conditional and reversible activation of class A and B G protein-coupled receptors using tethered pharmacology, Podewin, T.#; Ast, J.#; Broichhagen, J.#; Fine, N. H. F.; Nasteska, D.; Leippe, P.; Gailer, M.; Buenaventura, T.; Kanda, N.; Jones, B. J.; M’Kadmi, C.; Baneres, J.-L.; Marie, J.; Tomas, A.; Trauner, D.; Hoffmann-Röder, A.; Hodson, D. J., ACS Cent. Sci. 2018, 4, 166–179. 

​

22. Optical Control of a Biological Reaction-Diffusion System, Glock, P.; Broichhagen, J.; Kretschmer, S., Blumhardt, P.; Müksch, J.; Trauner, D.; Schwille, P., Angew. Chem. Int. Ed. 2018, 57, 2362–2366; Optical Control of a Biological Reaction-Diffusion System, Glock, P.; Broichhagen, J.; Kretschmer, S., Blumhardt, P.; Müksch, J.; Trauner, D.; Schwille, P., Angew. Chem. 2018, 130, 2386–2390.

​

21. Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor, Berry, H. M.; Holt, A.; Levitz, J.; Broichhagen, J.; Gaub, B. M.; Visel, M.; Stanley, C.; Kim, Y. J.; Cao, K.; Kramer, R. H.; Trauner, D.; Flannery, J.; Isacoff, E. Y., Nat. Commun. 2017, 8, 1862.

​

20. Optical control of GPR40 signalling in pancreatic β-cells, Frank, J.; Yushchenko, D.; Fine, N. H. F.; Duca, M.; Citir, M.; Broichhagen, J.; Hodson, D. J.; Schultz, C.; Trauner, D., Chem. Sci. 2017, 8, 7604–7610.

​

19. Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor, Jones, B. J.; Scopelliti, R.; Bloom, S. R.; Tomas, A.; Hodson, D. J.*; Broichhagen, J.*, ChemistryOpen 2017, 6, 501–505.

​

18. Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone, Podewin, T.#; Broichhagen, J.#; Frost, C.; Groneberg, D.; Ast, J.; Meyer-Berg, H.; Fine, N. H. F.; Friebe, A.; Zacharias, M.; Hodson, D. J.; Trauner, D.; Hoffmann-Röder, A., Chem. Sci. 2017, 8, 4644–4653.

​

17. Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors, Levitz, J.#; Broichhagen, J.#; Leippe, P.; Konrad, D.; Trauner, D.; Isacoff, E. Y., Proc. Natl. Acad. Sci. USA 2017, 114, E3546–E3554. 

​

16. Remote control of glucose homeostasis in vivousing photopharmacology, Mehta, Z. B.#; Johnston, N. R.#; Nguyen-Tu, M.-S.#; Broichhagen, J.; Schultz, P.; Larner, D. P.; Leclerc, I.; Trauner, D.; Rutter, G. A.; Hodson, D. J., Sci. Rep. 2017, 7, 291.

​

15. Beta cell hubs dictate pancreatic islet responses to glucose, Johnston, N. R.; Mitchell, R. K.; Haythorne, E.; Paiva Pessoa, M.-R., Semplici, F.; Ferrer, J.; Piemonti, L.; Marchetti, P.; Bugliani, M.; Bosco, D.; Berishvili, E.; Duncanson, P.; Watkinson, M.; Broichhagen, J.; Trauner, D.; Rutter, G. A.; Hodson, D. J., Cell Metab. 2016, 24, 1–13.

​

14. Allosteric Optical Control of a Class B G-Protein-Coupled Receptor, Broichhagen, J.; von Ohlen, Y.; Johnston, N. R.; Meyer-Berg, H.; Jones, B. J.; Bloom, S. R.; Rutter, G. A.; Trauner, D.; Hodson, D. J., Angew. Chem. Int. Ed. 2016, 55, 5865–5868; Allosterische optische Steuerung eines Klasse-B-G-Protein-gekoppelten Rezeptors, Broichhagen, J.; von Ohlen, Y.; Johnston, N. R.; Meyer-Berg, H.; Jones, B. J.; Bloom, S. R.; Rutter, G. A.; Trauner, D.; Hodson, D. J., Angew. Chem. 2016, 128, 5961–5965.

​

13. 6-(6-(Pyridin-2-yl)-1,2,4,5-tetrazin-3-yl)pyridin-3-amine monohydrate, Broichhagen, J.; Klingl, Y. E.; Trauner, D.; Mayer, P., Acta Cryst. 2016, E72, 238–240.

​

12. Optical Control of Insulin Release Using an Incretin Switch, Broichhagen, J.#; Podewin, T.#; Meyer-Berg, H.; von Ohlen, Y.; Johnston, N. R.; Jones, B. J.; Bloom, S. R.; Rutter, G. A.; Hoffmann-Röder, A.; Hodson, D. J.; Trauner, D., Angew. Chem. Int. Ed. 2015, 54, 15565–15569; Optische Kontrolle der Insulinsekretion mit einem Inkretinschalter, Broichhagen, J.#; Podewin, T.#; Meyer-Berg, H.; von Ohlen, Y.; Johnston, N. R.; Jones, B. J.; Bloom, S. R.; Rutter, G. A.; Hoffmann-Röder, A.; Hodson, D. J.; Trauner, D., Angew. Chem. 2015, 127, 15786–15790.

​

11. Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand, Broichhagen, J.#; Damijonaitis, A.#; Levitz, J.#; Sokol, K. R.; Leippe, P.; Konrad, D.; Isacoff, E. Y.; Trauner, D., ACS Cent. Sci. 2015, 1, 383–393. 

​

10. A roadmap to success in photopharmacology, Broichhagen, J.; Frank, J. A.; Trauner D., Acc. Chem. Res. 2015, 48, 1947–1960.

​

9.   Azobenzene-based inhibitors of human carbonic anhydrase II, Runtsch, L. S.; Barber, D. M.; Mayer, P.; Groll, M.; Trauner, D.*; Broichhagen, J.*, Beilstein J. Org. Chem. 2015, 11, 1129–1135.

​

8.   Crystal structure of (E)-1,2-bis(4-bromo-2,6-difluorophenyl)diazene, Broichhagen, J.; Woodmansee, D. H.; Trauner, D.; Mayer, P., Acta Cryst. 2015, E71, o459–o460.

​

7.   A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function, Broichhagen, J.; Frank, J. A.; Johnston, N. R.; Mitchell, R. K.; Smid, K.; Marchetti, P.; Bugliani, M.; Rutter, G. A.; Trauner, D.; Hodson, D. J., Chem. Commun. 2015, 51, 6018–6021. 

​

6.   AzoCholine enables optical control of alpha 7 nicotinic acetylcholine receptors in neural networks,Damijonaitis, A.; Broichhagen, J.; Hüll, K.; Nagpal, J.; Laprell, L.; Woodmansee, D. H.; Urushima, T.; Schönberger, M.; Rafiq, A.; Sumser, M. P.; Kummer, W.; Gottschalk, A.; Trauner, D., ACS Chem. Neurosci. 2015, 5, 701–707.

​

5.   The in vivo chemistry of photochromic tethered ligands, Broichhagen, J.; Trauner, D., Curr. Opin. Chem. Biol. 2014, 21, 121–127.

​

4.   Optical control of insulin release using a photoswitchable sulfonylurea, Broichhagen, J.; Schönberger, M.; Cork, S. C.; Frank, J. A.; Marchetti, P.; Bugliani, A. M.; Shapiro, A. M. J.; Trapp, S.; Rutter, G. A.; Hodson, D. J.; Trauner, D., Nat. Commun. 2014, 5, 5116.

​

3.   Optical Control of Acetylcholinesterase with a Tacrine Switch, Broichhagen, J.; Jurastow, I.; Iwan, K.; Kummer, W.; Trauner, D., Angew. Chem. Int. Ed. 2014, 53, 7657-7660; Optische Kontrolle der Acetylcholinesterase mit einem schaltbaren Tacrin, Broichhagen, J.; Jurastow, I.; Iwan, K.; Kummer, W.; Trauner, D., Angew. Chem. 2014, 126, 7788–7792.

​

2.   Bilirubin in a New Light, Broichhagen, J.; Trauner, D., Angew. Chem. Int. Ed. 2013, 52, 13868-13870; Bilirubin in einem neuen Licht, Broichhagen, J.; Trauner, D., Angew. Chem. 2013, 125, 14112–14114.

​

1.   Strain-Promoted Alkyne Azide Cycloaddition for the Functionalization of Poly(amide)-Based Dendrons and Dendrimers, Ornelas, C.; Broichhagen, J.; Weck, M., J. Am. Chem. Soc. 2010, 132, 3923–3931.

​

# these authors contributed equally

* corresponding author